The world's best racehorse figures among 46 entries made for the £1.3 million event at Ascot on October 20, where he will be bidding for a second success on British Champions Day after a four-length win in last season's Queen Elizabeth II Stakes.
Camelot is one of 13 entries for Aidan O'Brien, with other notable names including the likes of St Nicholas Abbey, Imperial Monarch and Power.
On the same card, the £1 million Group 1 Queen Elizabeth II Stakes, sponsored by Qipco, has attracted 37 entries including Beauty Parlour, a new addition to the team at the yard of Frankel's trainer Sir Henry Cecil.
Europe's richest race over a mile could see Excelebration finally emerge from Frankel's shadow, while other exciting entries include Fallen For You and Farhh.
Rod Street, chief executive of British Champions Series Limited, said: "We could not have hoped for better entries and they set the second edition of Qipco British Champions Day up to be a 'must-see' event like last year's.
"Frankel's final racecourse appearance will, of course, crown the day and he could face his biggest ever test in the Qipco Champion Stakes, while his likely absence from the Queen Elizabeth II Stakes should make Europe's richest mile race an ultra-competitive affair."
Darley July Cup winner Mayson, recently purchased by Cheveley Park Stud, heads 55 entries for the £250,000 Group 2 British Champions Sprint Stakes over 6f.
Last year's winner Dancing Rain is among 33 entries for the £250,000 Group 2 Qipco British Champions Fillies' And Mares' Stakes run over 1m 4f.
Gold Cup winner Colour Vision headlines 42 entries for the £200,000 Group 3 British Champions Long Distance Cup, run over 2m.
The two Group 2 races and one Group 3 contest all carry Group 1 conditions, with no penalties and prize-money consistent with Group 1 races.
